Category Archives: Dual-Specificity Phosphatase

The very first description of Hippo signaling in mammals a little more than 10 years ago showed a striking phenotype in the liver, linking the role of this signaling pathway to organ size control and carcinogenesis. functions. We format open … Continue reading →

The liver isn’t just involved in rate of metabolism and detoxification, but also participate in innate immune function and thus exposed to frequent target Thus, they are the frequent target of physical injury. they are also carcinogenic and cause liver … Continue reading →

Supplementary Materials Appendix EMBJ-39-e102374-s001. of the permanent tooth, triggering initiation of its development. Consequently, our findings identified biomechanical stress\associated Wnt modulation as a critical initiator of organ renewal, possibly shedding light on the mechanisms of integumentary organ regeneration. hybridization (ISH) … Continue reading →

Supplementary MaterialsSupplementary Details. results show that even in the absence of any inflammatory stimulus, mechanical compression alone is sufficient to induce an asthma-like molecular signature. and as a peripheral gene were validated by real-time RT-PCR in impartial samples (Supplementary Fig.?S2). … Continue reading →